PREPRINTS
Wang Y*, Yemelyanov A*, Go CD, Kim S, Quinn JM, Flozak AS, Le PM, Liang S, Claude-Gingras A, Ikura M, Ishiyama N, Gottardi CJ. Alpha-catenin mechanosensitivity as a route to cytokinesis failure through sequestration of LZTS2. bioRxiv. 2023 Aug 26:2023.08.25.554884. doi: 10.1101/2023.08.25.554884. Preprint. PMID: 37662204
2024
Quinn, JM*, Wang, Y.*, Wood, MN*, Flozak, AS, Le, PM, Yemelyanov, A., Oakes, PW and CJ Gottardi. 2024. α-catenin middle and actin-binding domain unfolding mutants differentially impact epithelial strength and sheet migration. 2024. Mol Biol Cell Mar 20:mbcE23010036. doi: 10.1091/
mbc.E23-01-0036. PMID: 38507238.
mbc.E23-01-0036. PMID: 38507238.
2023
Han, SH, GR Scott Budinger, CJ Gottardi. 2023. Alveolar epithelial regeneration in the elderly. J. Clinical Investigation. Oct 16th; 133 (20):e170504
PMID: 37843280.
PMID: 37843280.
Harmon, R and C.J.Gottardi. 2023. Endoplasmic reticulum tethering by desmosomes. Nat. Cell Biol. 2023 Jun;25(6):796-797. doi: 10.1038/s41556-023-01144-6. PMID: 37291268.
Dada, L. A, Welch, L. C., Magnani N.D., Ren Z., Han, H., Brazee P.L., Celli D., Flozak A.S., Weng A., Maciel-Herrerias M., Kryvenko V., Vadász I., Runyan C.E., Abdala-Valencia H., Shigemura M., Casalino-Matsuda M.S., Misharin A.V., Budinger G.R.S., *Gottardi C.J., *Sznajder J.I. 2023. Hypercapnia alters stroma-derived Wnt production to limit β-catenin-signaling and proliferation in alveolar type 2 cells. JCI Insight, Feb 22;8(4)e159331. PMID33626234.
2022
Huang CF, Gottardi CJ*, Mrksich, M*. Sci Rep. 2022. Tyrosine phosphatase activity is restricted by basic charge substituting mutation of substrates. Sep 5;12(1):15095. Doi:10.1038/s41598-022-19133-4. PMID: 36064958.
Weng A, Rabin, E.E., Flozak, A.S., Chiarella, S.E., Piseaux-Aillon, R and Gottardi CJ. 2022. Alpha-T-catenin is expressed in peripheral nerves as a constituent of Schwann cell adherens junctions. Biol Open. 2022 Nov 24:bio bio.059634. doi: 10.1242/bio.059634 PMID: 36420826.
Weng A, Maciel-Herrerias M, Watanabe S, Welch L, Flozak AS, Grant RA, Piseaux Aillon R, Dada L, Han SH, Hinchcliff M, Misharin AV, Budinger GRS and Gottardi CJ. 2022. Lung injury induces alveolar epithelial type 2 cell hypertrophy and polyploidy with implications for repair and regeneration.
Am J Res Cell Mol Biol. Feb 24. doi: 10.1165/rcmb.2021-0356OC. Online ahead of print. With Editorial Commentary.
Am J Res Cell Mol Biol. Feb 24. doi: 10.1165/rcmb.2021-0356OC. Online ahead of print. With Editorial Commentary.
2021
Watanabe S, Markov NS, Lu Z, Piseaux Aillon R, Soberanes S, Runyan CE, Ren Z, Grant RA, Maciel M, Abdala-Valencia H, Politanska Y, Nam K, Sichizya L, Kihshen HG, Joshi N, McQuattie-Pimentel AC, Gruner KA, Jain M, Sznajder JI, Morimoto RI, Reyfman PA, Gottardi CJ, Budinger GRS, Misharin AV. 2021. Resetting proteostasis with ISRIB promotes epithelial differentiation to attenuate pulmonary fibrosis. Proc Natl Acad Sci U S A. May 18;118(20) PMC8157939.
2020
Gottardi CJ, Luxton GWG. 2020. Nesprin-2G tension fine-tunes Wnt/beta-catenin signaling. J Cell Biol. 2020 Oct 5;219(10):e202009042.
doi: 10.1083/jcb.202009042. PMID: 32966550
doi: 10.1083/jcb.202009042. PMID: 32966550
2019
Reyfman PA, Walter JM, Joshi N, Anekalla KR, McQuattie-Pimentel AC, Chiu S, Fernandez R, Akbarpour M, Chen CI, Ren Z, Verma R, Abdala-Valencia H, Nam K, Chi M, Han S, Gonzalez-Gonzalez FJ, Soberanes S, Watanabe S, Williams KJN, Flozak AS, Nicholson TT, Morgan VK, Winter DR, Hinchcliff M, Hrusch CL, Guzy RD, Bonham CA, Sperling AI, Bag R, Hamanaka RB, Mutlu GM, Yeldandi AV, Marshall SA, Shilatifard A, Amaral LAN, Perlman H, Sznajder JI, Argento AC, Gillespie CT, Dematte J, Jain M, Singer BD, Ridge KM, Lam AP, Bharat A, Bhorade SM, Gottardi CJ, Budinger GRS, Misharin AV. 2019. Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis. Am. J. Respir. Crit. Care Med.
Jun 15;199(12):1517-1536. PMC6580683
Jun 15;199(12):1517-1536. PMC6580683
Malsin ES, Kim S, Lam AP, Gottardi CJ. 2019. Macrophages as a Source and Recipient of Wnt Signals. Front Immunol. 2019 Jul 31;10:1813. doi: 10.3389/fimmu.2019.01813. eCollection 2019.PMID: 31417574
Reyfman PA, Gottardi CJ. 2019. Idiopathic Pulmonary Fibrosis and Lung Cancer: Finding Similarities within Differences.
Am J Respir Cell Mol Biol. 2019 Dec;61(6):667-668. doi: 10.1165/rcmb.2019-0172ED. PMID: 31167078
Am J Respir Cell Mol Biol. 2019 Dec;61(6):667-668. doi: 10.1165/rcmb.2019-0172ED. PMID: 31167078
2018
Ishiyama N, Sarpal R, Wood MN, Barrick SK, Nishikawa T, Hayashi H, Kobb AB, Flozak AS, Yemelyanov A, Fernandez-Gonzalez R, Yonemura S, Leckband DE, Gottardi CJ, Tepass U, Ikura M. 2018. Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions.. Nat. Commun. Nov 30;9(1):5121.